---
title: Is it possible to cover cell spheroids with VitroGel® and apply differentiation media on top?
description: Yes, the medium on top can penetrate through the hydrogel.
url: "https://www.thewellbio.com/docs/is-it-possible-to-cover-cell-spheroids-with-vitrogel-and-apply-differentiation-media-on-top/"
updated: "2024-08-19"
category: "3D Cell Models & Functional Assays"
tags:
  - Spheroid
---

# Is it possible to cover cell spheroids with VitroGel® and apply differentiation media on top?

Yes, the medium on top can penetrate through the hydrogel.