CytoGrow™ Recombinant IL-18 (Human), CHO, Tag Free
Recombinant human IL-18 is a pro-inflammatory cytokine produced in CHO cells, ensuring authentic glycosylation and proper protein folding. This tag-free version closely mimics the native human IL-18, making it ideal for use in immunological assays, inflammation studies, and cytokine signaling research.
IL-18 plays a critical role in both innate and adaptive immunity by inducing IFN-γ production, especially in synergy with IL-12. It activates NK cells and T cells, enhancing their cytotoxic activity and promoting Th1-type immune responses. IL-18 is widely studied in the context of infectious disease, autoimmune disorders, cancer immunology, and inflammatory conditions.
Specifications
Synonym: | Interleukin-18; Iboctadekin; Interferon gamma-inducing factor; IFN-gamma-inducing factor; Interleukin-1 gamma; IL-1 gamma;GIF; IL-18; IL-1g; IL1F4; MG/VAIL C12320 |
Species: | Human |
Expression System: | Chinese hamster ovary cells (CHO) |
Endotoxin: | ≤10 EU/mg |
Appearance: | White powder, colorless clear liquid after reconstitution |
Formulation | Lyophilized from a 0.22 μm filtered solution containing PBS, 5% mannitol, and 0.01% Tween 80 |
Reconstitution: | Recommended to redissolve in sterile deionized water |
Shipping: | Ships overnight |
Storage and Stability: | Store in a manual defrost freezer and avoid repeated freeze-thaw cycles. Lyophilized state: 36 months at -20°C to -80°C After reconstitution and under sterile conditions: 6 months at -20°C to -80°C 7-10 days at 2°C to 8°C |
Data and Bioactivity
