Category Archives: Webinars

A Novel Pre-Clinical Model of the Normal Human Breast

Key Takeaways: Normal breast tissue can be cultured for 7 days with no changes in proliferation or viability. Tissue maintains expression of oestrogen and progesterone receptors and remains responsive to hormones. Using this model, we aim to identify mechanisms of resistance to preventative agents and screen for novel approaches to breast cancer risk-reduction that could […]

Advanced Cell Mobility Studies Using the Xeno-free Vitrogel®-Based Cell Invasion Assay Kits

Dr. Alejandra Ferrer Díaz earned her doctorate from Rutgers University, where she studied the interactions between mesenchymal stem cells and breast cancer cells in the bone marrow microenvironment. She is a research scientist at TheWell Bioscience, primarily focusing on developing and refining cell-based assays and co-culture models using the VitroGel hydrogel system. Webinar Summary: Advanced […]

Development of In Vitro Intestinal Model With Macrovascular Endothelium: Compare Animal-based and Xeno-free ECM Platforms

Scarlett Zeiringer is a PhD student at the University of Graz, Institute of Pharmaceutical Sciences, Austria. She works in Prof. Eva Roblegg’s lab at the Institute of Pharmaceutical Technology and Biopharmacy, where she is working on in vitro cell models to study the fate of drug delivery systems. In particular, she aims to develop advanced […]

Scale-Up 3D Model Drug Screening Using a Robotic Platform with Xeno-Free Hydrogel

Webinar Summary: Scale-Up 3D model Drug Screening Using a Robotic Platform with Xeno-Free Hydrogel Automating drug screening on the 3D cell models can significantly reduce the time and effort involved and increase assay precision and throughput. Here, we describe methods for the generation and toxicology screening of hydrogel-based 3D models using an integrated system – […]

Comparative Study of Animal-derived ECMs and VitroGel® Hydrogel for hiPSC Maintenance and Intestinal Organoid Generation

Dr. Janny Piñeiro Llanes is a Post Doctoral Associate in the Department of Pharmaceutics at the University of Florida. Currently, she joined Dr. Cristofoletti’s Laboratory at the Center for Pharmacometrics & Systems Pharmacology to develop and optimize organotypic and micro-physiological systems for in vitro testing of pharmacological compounds. Specifically, she aims to extract, from in […]

Using Animal-Free VitroGel Hydrogel in Comparison to Animal-based Extracellular Matrix for Xenograft (PDX & CDX) Models

Webinar Abstract: Patient-derived xenografts (PDX) and cell-derived xenografts (CDX) are important tools for studying tumor behavior and drug responsiveness for pre-clinical oncology studies. PDX and CDX models can accelerate the development of new cancer treatments and improve our understanding of tumor biology and efficacy for diverse patients to individualized patients’ specific cancer.   Animal-based extracellular […]

Patient-Derived Tumoroids in 3D Xeno-Free Hydrogel with Automated Biomarker Detection

Abstract 3D cell models like organoid and patient-derived tumoroid are becoming increasingly important for personalized medicine, drug screening and cell therapy. Such 3D models are highly relied on for microenvironment recapitulation.  A reliable xeno-free hydrogel system that can closely mimic the natural extracellular matrix (ECM) is extremely important to replace the animal-based extracellular matrix to […]