Category Archives: White Papers

Patient-Derived Xenograft Using Xeno-Free VitroGel System in Comparison to Animal-based Matrigel

Introduction Patient-derived xenografts are becoming state-of-the-art for studying tumor behavior and drug responsiveness in a salient environment1. A patient-derived xenograft (PDX) is obtained when a tumor sample is removed from a patient, implanted into an immunosuppressed murine host, and then queried for cellular or molecular characteristics that could be of therapeutic value to the patient. […]

Comparing the Xeno-Free VitroGel to Animal-Based Matrigel for Xenograft Studies

Introduction A cell-derived xenograft (CDX) model is the gold standard for anti-cancer therapies. The response of xenografts obtained in immune-deficient animals in drug testing is comparable to that in clinical practice, which makes xenograft models robust research tools in oncology1. In addition, over the past decades, patient-derived xenograft (PDX) models have emerged for precision medicine […]