Introduction Organoids have become valuable in vitro models for studying human biology, disease, and drug responses because they better mimic native tissue architecture than conventional 2D cell cultures. However, most organoid workflows still rely on animal-derived extracellular matrices (ECMs), such as Matrigel®, which introduce batch-to-batch variability, undefined composition, and xenogeneic components, thereby compromising reproducibility and […]
Background: Organoids are 3D self-organizing tissue models that closely mimic the architecture and function of native organs. Epithelial polarity is a fundamental feature of intestinal organoids, governing nutrient absorption, drug transport, and barrier function. Conventional Matrigel-grown intestinal organoids exhibit an apical-in orientation, restricting direct access to the absorptive epithelial surface. Apical-out intestinal organoids expose the […]
Proprietary small-molecule cocktail significantly improves post-passaging recovery, cryopreservation outcomes, and long-term expansion of sensitive cell cultures. MONMOUTH JUNCTION, N.J., July7, 2026 — TheWell Bioscience, a leader in xeno-free 3D cell culture technologies, today announced the commercial launch of RocketCell™ Cell Viability Enhancer, a proprietary small-molecule formulation designed to maximize cell survival, metabolic recovery, and growth […]
VitroGel® MSC hydrogel enhances anti-inflammatory response in human gingiva-derived mesenchymal stromal cells (hG-MSCs), offering a promising approach to optimize cell-based therapies for inflammatory diseases. Mesenchymal stromal cells (MSCs) have emerged as promising candidates for regenerative medicine due to their remarkable ability to modulate the immune system and promote tissue repair. These cells can be isolated […]
Discover how these solutions work together to simplify and streamline stem cell research.
Join us at the International Society for Stem Cell Research 2026 at Palais des congrès de Montréal, Canada, from July 8-10, 2026. Advance stem cell research with an integrated platform designed to support every stage of your workflow. VitroGel® synthetic hydrogels, RocketCell™ media, CytoGrow™ growth factors, VitroPrime™ cultureware, and Cyto3D® analysis solutions work together to […]
The PAL Lab at Temple University, led by Ajay Pal, Ph.D. has initiated a research study to evaluate VitroGel® NEURON, a fully synthetic hydrogel free of animal-derived components, as an injectable biomaterial for spinal cord injury repair. Spinal cord injury remains a devastating condition with limited treatment options, often resulting in permanent neurological deficits and […]
Abstract: Human induced pluripotent stem cells (iPSCs) offer a powerful launch point to study the cellular mechanisms of the developing embryo and the formation of organ systems. Further, they provide an invaluable tool for developing patient-specific models for studying disease processes and drug discovery. However, many in vitro studies have been conducted in 2D, overlooking […]
Using TheWell Bioscience’s complete xeno-free 3D cell culture platform, we offer customized services that help reduce setup time, lower development costs, and accelerate your research. We work with your goals and budget to establish an optimized workflow, so you can focus on generating reliable and reproducible results. In addition, our scientists can work with you […]
