Author Archives: Kyra Baricaua

Evaluating Spheroid Invasion with VitroGel® Hydrogel Matrix in VitroPrime™ Ultra-Low Attachment, U-Bottom, 96-well Plate

Introduction Spheroid invasion assays offer a physiologically relevant three-dimensional (3D) in vitro model for studying cancer cell behavior, surpassing the limitations of traditional two-dimensional (2D) cultures [1]. Spheroids are compact cell aggregates that recapitulate critical in vivo features, including cell–cell and cell–matrix interactions, as well as nutrient and oxygen gradients providing a more accurate representation […]

NEW PRODUCT: VitroGel® NEURON

TheWell Bioscience Unveils VitroGel® NEURON: A Breakthrough in 3D and 2D Neuron Culture TheWell Bioscience proudly launches VitroGel® NEURON, a ready-to-use, xeno-free hydrogel system designed to support both 2D and 3D cultures of neural stem cells and neurons. This innovative product aims to provide researchers with an animal-free, reliable, and consistent platform for neural cell […]

The International Society for Stem Cell Research (ISSCR) – 2025

We are excited to announce that TheWell Bioscience will be exhibiting at the ISSCR 2025 Annual Meeting—the premier global event for stem cell and regenerative medicine research. Join us and thousands of scientists, clinicians, and industry leaders as we explore the cutting edge of stem cell science and shape the future of biomedical innovation. Discover […]

VitroGel® at the Frontlines: Enabling 3D Modeling of Venous Invasion in Pancreatic Cancer

This study leveraged VitroGel®’s hydrogel system to model the tumor microenvironment and uncover the role of TIMP1 in driving venous invasion in pancreatic cancer. Hydrogel: VitroGel® Hydrogel Matrix (VHM01) Pancreatic ductal adenocarcinoma (PDAC) is characterized by its aggressive nature and poor prognosis, often driven by early vascular invasion and metastasis. In this study, researchers focused […]

Bringing the Brain to the Bench: A Microfluidic BBB Model for Tumor Interaction Studies

VitroGel® IKVAV was a key component that enabled stable vessel formation, proper cellular organization and functional BBB behavior in the 3D microfluidic model. Hydrogel: VitroGel® IKVAV (Cat. No: TWG007) The blood-brain barrier (BBB) presents a major challenge in neuro-oncology and CNS drug development due to its highly selective nature, which restricts the passage of most […]