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VitroGel® Hydrogel: An excellent alternative to animal-based ECM for 3D cell culture
Go beyond animal-based ECMs with VitroGel® – a xeno-free, biofunctional, easy-to-use, hydrogel that can help translate your cell culture assays toward advanced biomedicine.
VitroGel® maintains a liquid form at room temperature for easy handling and operation, and closely mimics the natural ECM environment without any animal or human components.
VitroGel® system is a superior platform compared to animal-based ECM for 3D cell culture, trusted by over 1,000 research labs worldwide for advancing cell culture models, including 2D/3D, organoids, stem cells, neurons, MSCs, spheroids, functional assays, co-culture, PDX, and CDX in vivo applications, among many others.
Xeno-free and Synthetic
100% animal/human origin-free synthetic hydrogel system.
Room Temperature Operation
20-min protocol. Gelation by mixing not temperature dependent.
Biofunctional and Biocompatible
Optimized with multi-functional ligands for many cell types. Biocompatible material suitable for xenograft and in vivo applications.
Reproducible Assays
Batch-to-batch consistency ensures reproducible results. Available for GMP process.
Injectable
Long-term injectability after gelation with no needle clogging. Unique shear-thinning and rapid recovery properties for excellent cell retention.
Ethical
Unlike animal-based ECM, no mice are sacrificed in product manufacturing..
VitroGel® is versatile, covering many animal-based ECM applications and offering significant advantages to bridge in vitro and in vivo studies.
Apical-out organoids cultured in VitroGel® ORGANOID.
(A) Indicates a young mouse intestinal organoid with apical-out polarity cultured in VitroGel® ORGANOID-3. (B) A mature intestinal organoid cultured in VitroGel® ORGANOID, maintained apical-out polarity while developing intestinal lumen structure (C) Intestinal organoid cultured in Matrigel® demonstrated apical-in polarity. Green color represents Phalloidin staining, an apical locator.DAPI (blue) – stains cell nuclei.
Human mammary breast cancer cells cultured in VitroGel® Hydrogel Matrix and Matrigel, a natural Extracellular Matrix (ECM) hydrogel.
The images above are 3D cell cultures of human mammary breast cancer cells (MCF-7) on day 7 in VitroGel® Hydrogel Matrix and Matrigel, a natural ECM-based hydrogel from Engelbreth-Holm-Swarm murine sarcoma.
Start with the right ECM for your cell culture research.
Discover the 20+ advantages of VitroGel® over animal-based ECM offering easier, faster, and more reproducible cell culture with lab automation capability.
