IL-4 (Human), Recombinant Protein, CHO, Tag Free
Premium CytoGrow™ growth factor suitable for immunology research, allergy and asthma models, inflammation studies, and therapeutic development.
CytoGrow™ Recombinant IL-4 (Human), CHO, Tag Free
Recombinant human interleukin-4 (IL-4) is produced in CHO cells in a tag-free format, ensuring proper folding, glycosylation, and high biological activity. IL-4 is a pleiotropic cytokine critical for immune regulation, particularly in driving Th2 cell differentiation and modulating antibody class switching.
Secreted by activated T cells, mast cells, and basophils, IL-4 promotes B cell proliferation, enhances IgE and IgG1 production, and regulates macrophage activation toward an anti-inflammatory (M2) phenotype. It plays a pivotal role in allergy, asthma, and tissue repair processes. Recombinant human IL-4 is widely used in immunology research, allergy and inflammation studies, and therapeutic development.
| Synonym: | Interleukin-4; IL-4; B-Cell Stimulatory Factor 1; BSF-1; Binetrakin; Lymphocyte Stimulatory Factor 1; Pitrakinra; IL4 |
| Species: | Human |
| Expression System: | Chinese hamster ovary cells (CHO) |
| Endotoxin: | ≤10 EU/mg |
| Appearance: | White powder, colorless clear liquid after reconstitution |
| Formulation | Lyophilized from a 0.22 μm filtered solution containing PBS, 5% mannitol, and 0.01% Tween 80 |
| Reconstitution: | Recommended to redissolve in sterile deionized water |
| Shipping: | Shipped with ice pack |
| Storage and Stability: | Store in a manual defrost freezer and avoid repeated freeze-thaw cycles. Lyophilized state: 36 months at -20°C to -80°C After reconstitution and under sterile conditions: 6 months at -20°C to -80°C 7-10 days at 2°C to 8°C |
Resources
Booklet – CytoGrow Growth Factors
Material Safety Data Sheet (MSDS)
Data and Bioactivity
| Size | 1 μg, 10 µg, 50 μg, 1 mg, 10 mg, 100 mg, 1 g, 1 mL, 10 mL |
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