Recombinant human R-Spondin1 is expressed in CHO cells to ensure proper folding and authentic mammalian post-translational modifications. This tag-free protein retains the native structure and high bioactivity of human R-Spondin1, making it suitable for diverse applications in cell signaling and developmental biology research.

R-Spondin1 is a secreted protein that acts as a potent activator of the Wnt/β-catenin signaling pathway, playing a critical role in stem cell proliferation, tissue regeneration, and organ development. It enhances Wnt signaling by binding to LGR receptors and modulating receptor activity. Recombinant human R-Spondin1 is widely used in studies of stem cell biology, regenerative medicine, and cancer research.