CytoGrow™ Recombinant DKK-1 (Human), CHO, Tag Free
Recombinant human Dickkopf-related protein 1 (DKK-1) is produced in CHO cells to provide high purity, correct folding, and reliable biological activity. Supplied in a tag-free format, this protein preserves its native sequence, making it suitable for studies of Wnt signaling and bone biology.
DKK-1 is a secreted glycoprotein that functions as an antagonist of the Wnt/β-catenin signaling pathway. It plays a critical role in embryonic development, bone formation, and regulation of osteoblast and osteoclast activity. DKK-1 is also studied in the context of cancer, osteoporosis, and inflammatory diseases.
Specifications
Synonym: | NA |
Species: | Human |
Expression System: | Chinese hamster ovary cells (CHO) |
Endotoxin: | ≤10 EU/mg |
Appearance: | White powder, colorless liquid after reconstitution |
Formulation | Lyophilized from a 0.22 μm filtered solution containing PBS, 5% mannitol, and 0.01%Tween 80 |
Reconstitution: | Recommended to redissolve in sterile deionized water. |
Shipping: | Ships overnight |
Storage and Stability: | Store in a manual defrost freezer and avoid repeated freeze-thaw cycles. Lyophilized state: 36 months at -20°C to -80°C After reconstitution and under sterile conditions: 6 months at -20°C to -80°C 7-10 days at 2°C to 8°C |
Data and Bioactivity
