GDF-8 (Human), Recombinant Protein, CHO, Tag Free
Premium CytoGrow™ growth factor suitable for muscle biology, regenerative medicine, metabolic research, and therapeutic development for muscle-related diseases
CytoGrow™ Recombinant GDF-8 (Human), CHO, Tag Free
Recombinant human growth differentiation factor 8 (GDF-8), also known as myostatin, is produced in CHO cells in a tag-free format, ensuring proper folding, glycosylation, and high biological activity. GDF-8 is a member of the TGF-β superfamily and functions as a negative regulator of skeletal muscle growth.
GDF-8 is secreted as a latent precursor that undergoes proteolytic processing to release the active mature dimer. It plays a critical role in muscle development, regeneration, and metabolic regulation. Loss of GDF-8 activity is associated with increased muscle mass, while overexpression contributes to muscle wasting. Recombinant human GDF-8 is widely used in muscle biology, metabolic research, regenerative medicine, and drug discovery targeting sarcopenia and muscular dystrophy.
| Synonym: | |
| Species: | Human |
| Expression System: | Chinese Hamster Ovary (CHO) |
| Endotoxin: | ≤10 EU/mg |
| Appearance: | White powder, colorless liquid after reconstitution |
| Formulation | Lyophilized from a 0.22 μm filtered solution containing 0.085% TFA, 30% CAN, and 5% MAnnitol |
| Reconstitution: | Recommended to redissolve in sterile deionized water |
| Shipping: | Ships overnight |
| Storage and Stability: | Store in a manual defrost freezer and avoid repeated freeze-thaw cycles. Lyophilized state: 36 months at -20°C to -80°C After reconstitution and under sterile conditions: 6 months at -20°C to -80°C 7-10 days at 2°C to 8°C |
Resources
Booklet – CytoGrow Growth Factors
Material Safety Data Sheet (MSDS)
Data and Bioactivity
Upload Image...
| Size | 1 μg, 10 µg, 50 μg, 1 mg, 100 mg, 1 g, 1 mL, 10 mL |
|---|
Related products
CytoGrow™ - Recombinant Proteins
Premium CytoGrow™ growth factor suitable for bone and cartilage research, fibrosis models, kidney development studies, regenerative medicine, and drug discovery.
CytoGrow™ - Recombinant Proteins
Premium CytoGrow™ growth factor suitable for developmental biology, neurobiology, skeletal development, angiogenesis, and cancer research.
CytoGrow™ - Recombinant Proteins
Premium CytoGrow™ growth factor suitable for developmental biology, epithelial tissue regeneration, organoid culture, stem cell differentiation, and regenerative medicine.
CytoGrow™ - Recombinant Proteins
Premium CytoGrow™ growth factor suitable for cell culture supplementation, wound healing research, epithelial biology, and cancer signaling studies.
CytoGrow™ - Recombinant Proteins
Premium CytoGrow™ growth factor suitable for stem cell culture, angiogenesis research, wound healing studies, and regenerative medicine.
CytoGrow™ - Recombinant Proteins
Premium CytoGrow™ growth factor suitable for cell culture coating, ECM research, wound healing, angiogenesis, tissue engineering, and regenerative medicine.
