CytoGrow™ Recombinant GM-CSF (Human), CHO, Tag Free
Recombinant human granulocyte-macrophage colony-stimulating factor (GM-CSF) is produced in CHO cells to ensure proper folding, glycosylation, and full biological activity. Supplied in a tag-free format, this cytokine preserves its native conformation, making it ideal for applications in immunology, hematopoiesis, and cell therapy research.
GM-CSF is a hematopoietic growth factor that regulates the survival, proliferation, and differentiation of granulocyte and macrophage progenitors. It also enhances the function of mature monocytes, macrophages, and dendritic cells, playing a critical role in host defense, inflammation, and immune regulation. Recombinant GM-CSF is widely used in immune cell culture, dendritic cell generation, and studies of hematopoietic and inflammatory pathways.
Specifications
Synonym: | Granulocyte-Macrophage Colony-Stimulating Factor; GM-CSF; Colony-Stimulating Factor; CSF; Molgramostin; Sargramostim; CSF2; GMCSF |
Species: | Human |
Expression System: | Chinese Hamster Ovary cell line (CHO) |
Endotoxin: | ≤10 EU/mg |
Appearance: | White powder, colorless liquid after reconstitution |
Formulation | Lyophilized from a 0.22 μm filtered solution containing PBS, 5% mannitol, and 0.01% Tween 80 |
Reconstitution: | Recommended to redissolve in sterile deionized water |
Shipping: | Ships overnight |
Storage and Stability: | Store in a manual defrost freezer and avoid repeated freeze-thaw cycles. Lyophilized state: 36 months at -20°C to -80°C After reconstitution and under sterile conditions: 6 months at -20°C to -80°C 7-10 days at 2°C to 8°C |