CytoGrow™ Recombinant GM-CSF (Mouse), CHO, Tag Free
Recombinant mouse granulocyte-macrophage colony-stimulating factor (GM-CSF) is produced in CHO cells in a tag-free format, ensuring native-like protein folding, glycosylation, and high biological activity. Mouse GM-CSF is a key cytokine involved in the regulation of immune and hematopoietic responses, promoting the survival, proliferation, and differentiation of myeloid progenitor cells.
Secreted by activated T cells, macrophages, endothelial cells, and fibroblasts, GM-CSF enhances the function of dendritic cells, neutrophils, and macrophages, playing an essential role in host defense and inflammation. It is widely used in mouse models to study hematopoiesis, autoimmune diseases, cancer, and inflammatory responses. Recombinant mouse GM-CSF is a valuable tool for in vivo and in vitro studies of immune regulation and therapeutic development.
Specifications
Synonym: | Granulocyte-Macrophage Colony-Stimulating Factor; GM-CSF; Colony-Stimulating Factor; CSF; Molgramostin; Sargramostim; CSF2; GMCSF |
Species: | Mouse |
Expression System: | Chinese Hamster Ovary cell line (CHO) |
Endotoxin: | ≤10 EU/mg |
Appearance: | White powder, colorless liquid after reconstitution |
Formulation | Lyophilized from a 0.22 μm filtered solution containing PBS, 5% mannitol, and 0.01% Tween 80 |
Reconstitution: | Recommended to redissolve in sterile deionized water |
Shipping: | Ships overnight |
Storage and Stability: | Store in a manual defrost freezer and avoid repeated freeze-thaw cycles. Lyophilized state: 36 months at -20°C to -80°C After reconstitution and under sterile conditions: 6 months at -20°C to -80°C 7-10 days at 2°C to 8°C |
Data and Bioactivity
