IGF-II (Human), Recombinant Protein, HEK293, Tag Free

Premium CytoGrow™ growth factor suitable for stem cell and organoid culture, developmental biology studies, metabolic regulation research, cancer and growth signaling models

CytoGrow™ Recombinant IGF-II (Human), HEK293, Tag Free

Recombinant human insulin-like growth factor II (IGF-II) is produced in HEK293 cells in a tag-free format, ensuring proper folding and human-like post-translational modifications. IGF-II is a mitogenic polypeptide hormone structurally related to insulin and IGF-I, playing an essential role in embryonic growth, tissue development, metabolism, and cell survival.

In humans, IGF-II is highly expressed during fetal development and contributes to cell proliferation, differentiation, and survival through binding to IGF receptors and insulin receptor isoforms. It is also implicated in metabolic regulation, stem cell biology, and cancer progression. Recombinant IGF-II is widely used in developmental biology studies, stem cell and organoid culture, metabolic research, and oncology models.

Specifications 

Synonym: 
Species:Human
Expression System:HEK 293
Endotoxin:≤10 EU/mg
Appearance:White powder, colorless liquid after reconstitution
Formulation Lyophilized from a 0.2 μm filtered solution containing TFA, ACN, 5% Trehalose
Reconstitution:Recommended to redissolve in 4 mM HCl
Shipping:Ships overnight
Storage and Stability:Store in a manual defrost freezer and avoid repeated freeze-thaw cycles.

Lyophilized state:
36 months at -20°C to -80°C

After reconstitution and under sterile conditions:
6 months at -20°C to -80°C
7-10 days at 2°C to 8°C

Resources


Booklet – CytoGrow Growth Factors

Product Data Sheet

Material Safety Data Sheet (MSDS)

Frequently Asked Questions 

Data and Bioactivity

CytoGrow-IGF-II-Bioactivity
Size

1 μg, 10 µg, 50 μg, 1 mg, 10 mg, 100 mg, 1 g, 1 mL, 10 mL