IL-12 (Human), Recombinant Protein, CHO, Tag Free
Premium CytoGrow™ growth factor suitable for immunology and inflammation research, Th1‑mediated immunity studies, NK cell function assays, cancer immunotherapy, cytokine signaling analysis, and autoimmune disease modeling.
CytoGrow™ Recombinant IL-12 (Human), CHO, Tag Free
Recombinant human IL-12 is a heterodimeric cytokine composed of p35 and p40 subunits, produced in CHO cells to ensure high bioactivity and authentic human-like post-translational modifications. This tag-free protein closely resembles the native form, making it ideal for sensitive immunological assays and cell signaling studies.
IL-12 plays a pivotal role in promoting the differentiation of naïve T cells into Th1 cells and enhancing the cytotoxic activity of natural killer (NK) cells and CD8⁺ T cells. It is a key regulator of cell-mediated immunity and is widely used in research involving immune activation, inflammation, cancer immunotherapy, and infectious diseases.
| Synonym: | Interleukin-12 subunit alpha; IL-12A; Cytotoxic lymphocyte maturation factor 35 kDa subunit; CLMF p35; IL-12 subunit p35; NK cell; IL12A ; NKSF1 stimulatory factor chain 1 |
| Species: | Human |
| Expression System: | Chinese Hamster Ovary cell line (CHO) |
| Endotoxin: | ≤10 EU/mg |
| Appearance: | White powder, colorless liquid after reconstitution |
| Formulation | Lyophilized from a 0.22 μm filtered solution containing PBS 5% mannitol, and 0.01% Tween 80 |
| Reconstitution: | Recommended to redissolve in sterile deionized water |
| Shipping: | Shipped with ice pack |
| Storage and Stability: | Store in a manual defrost freezer and avoid repeated freeze-thaw cycles. Lyophilized state: 36 months at -20°C to -80°C After reconstitution and under sterile conditions: 6 months at -20°C to -80°C 7-10 days at 2°C to 8°C |
Resources
Booklet – CytoGrow Growth Factors
Material Safety Data Sheet (MSDS)
Data and Bioactivity
| Size | 1 μg, 10 µg, 50 μg, 1 mg, 10 mg, 100 mg, 1 g, 1 mL, 10 mL |
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