IL-21 (Human), Recombinant Protein, CHO, hFC-Tag
Premium CytoGrow™ growth factor suitable for immuno-oncology, vaccine development, Fc fusion protein studies, autoimmune disease research, and therapeutic development.
CytoGrow™ Recombinant IL-21 (Human), CHO, hFC-Tag
Recombinant human IL-21 is a cytokine expressed in CHO cells and fused to a human Fc (hFC) tag to enhance protein stability, solubility, and in vivo half-life. The hFC tag also facilitates purification, detection, and receptor binding studies, while preserving the native bioactivity of IL-21.
IL-21 is produced by activated CD4⁺ T cells and is a key regulator of both innate and adaptive immune responses. It stimulates the proliferation and functional activity of NK cells, CD8⁺ T cells, and B cells, and is involved in antibody production, cytotoxic activity, and immune regulation. The Fc-tagged format is ideal for applications requiring increased molecular stability or Fc receptor engagement.
| Synonym: | Interleukin-21; IL-21; Za11; IL21 |
| Species: | Human |
| Expression System: | Chinese Hamster Ovary cell line (CHO) |
| Endotoxin: | ≤10 EU/mg |
| Appearance: | White powder, colorless liquid after reconstitution |
| Formulation | Lyophilized from a 0.2 μm filtered solution containing PBS 5% mannitol, and 0.01% Tween 80 |
| Reconstitution: | Recommended to redissolve in sterile deionized water |
| Shipping: | Shipped with ice pack |
| Storage and Stability: | Store in a manual defrost freezer and avoid repeated freeze-thaw cycles. Lyophilized state: 36 months at -20°C to -80°C After reconstitution and under sterile conditions: 6 months at -20°C to -80°C 7-10 days at 2°C to 8°C |
Resources
Booklet – CytoGrow Growth Factors
Material Safety Data Sheet (MSDS)
Data and Bioactivity
| Size | 1 μg, 10 µg, 50 μg, 1 mg, 10 mg, 100 mg, 1 g, 1 mL, 10 mL |
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