CytoGrow™ Recombinant IL-21 (Human), CHO, Tag Free
Recombinant human IL-21 is a glycoprotein cytokine expressed in CHO cells to ensure native-like folding and post-translational modifications. This tag-free format preserves the natural structure and activity of IL-21, making it suitable for cell-based assays and immunological studies where tag-free purity is critical.
IL-21 is primarily produced by activated CD4⁺ T cells and plays a pivotal role in regulating immune responses. It promotes the proliferation and function of NK cells, CD8⁺ T cells, and B cells, and is involved in antibody production, cytotoxicity, and immune memory. IL-21 is widely used in studies of cancer immunotherapy, chronic infection, and autoimmune disease.
Specifications
Synonym: | Interleukin-21; IL-21; Za11; IL21 |
Species: | Human |
Expression System: | Chinese Hamster Ovary cell line (CHO) |
Endotoxin: | ≤10 EU/mg |
Appearance: | White powder, colorless liquid after reconstitution |
Formulation | Lyophilized from a 0.22 μm filtered solution containing PBS 5% mannitol, and 0.01% Tween 80 |
Reconstitution: | Recommended to redissolve in sterile deionized water |
Shipping: | Ships overnight |
Storage and Stability: | Store in a manual defrost freezer and avoid repeated freeze-thaw cycles. Lyophilized state: 36 months at -20°C to -80°C After reconstitution and under sterile conditions: 6 months at -20°C to -80°C 7-10 days at 2°C to 8°C |
Data and Bioactivity
