IL-21 (Human), Recombinant Protein, CHO, Tag Free
Premium CytoGrow™ growth factor suitable for immuno-oncology, vaccine research, autoimmune disease models, T and B cell biology, and cytokine signaling studies.
CytoGrow™ Recombinant IL-21 (Human), CHO, Tag Free
Recombinant human IL-21 is a glycoprotein cytokine expressed in CHO cells to ensure native-like folding and post-translational modifications. This tag-free format preserves the natural structure and activity of IL-21, making it suitable for cell-based assays and immunological studies where tag-free purity is critical.
IL-21 is primarily produced by activated CD4⁺ T cells and plays a pivotal role in regulating immune responses. It promotes the proliferation and function of NK cells, CD8⁺ T cells, and B cells, and is involved in antibody production, cytotoxicity, and immune memory. IL-21 is widely used in studies of cancer immunotherapy, chronic infection, and autoimmune disease.
| Synonym: | Interleukin-21; IL-21; Za11; IL21 |
| Species: | Human |
| Expression System: | Chinese Hamster Ovary cell line (CHO) |
| Endotoxin: | ≤10 EU/mg |
| Appearance: | White powder, colorless liquid after reconstitution |
| Formulation | Lyophilized from a 0.22 μm filtered solution containing PBS 5% mannitol, and 0.01% Tween 80 |
| Reconstitution: | Recommended to redissolve in sterile deionized water |
| Shipping: | Shipped with ice pack |
| Storage and Stability: | Store in a manual defrost freezer and avoid repeated freeze-thaw cycles. Lyophilized state: 36 months at -20°C to -80°C After reconstitution and under sterile conditions: 6 months at -20°C to -80°C 7-10 days at 2°C to 8°C |
Resources
Booklet – CytoGrow Growth Factors
Material Safety Data Sheet (MSDS)
Data and Bioactivity
| Size | 1 μg, 10 µg, 50 μg, 1 mg, 10 mg, 100 mg, 1 g, 1 mL, 10 mL |
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