CytoGrow™ Recombinant IL-23 (Human), CHO, Tag Free
Recombinant human IL-23 is a heterodimeric cytokine composed of p19 and p40 subunits, expressed in CHO cells to ensure proper folding, glycosylation, and high biological activity. This tag-free format preserves the native structure of IL-23, making it ideal for immunological research and cell-based functional assays.
IL-23 plays a central role in the regulation of inflammatory responses and the maintenance of Th17 cells. It promotes the production of pro-inflammatory cytokines and is implicated in autoimmune diseases, chronic inflammation, and tumor progression. Recombinant IL-23 is widely used in studies of immune modulation, inflammatory signaling pathways, and autoimmune disease mechanisms.
Specifications
Synonym: | IL-23 p19/IL-12 p40; IL23; IL-23A; Interleukin 23; SGRF |
Species: | Human |
Expression System: | Chinese Hamster Ovary cell line (CHO) |
Endotoxin: | ≤10 EU/mg |
Appearance: | White powder, colorless liquid after reconstitution |
Formulation | Lyophilized from a 0.22 μm filtered solution containing PBS 5% mannitol, and 0.01% Tween 80 |
Reconstitution: | Recommended to redissolve in sterile deionized water |
Shipping: | Ships overnight |
Storage and Stability: | Store in a manual defrost freezer and avoid repeated freeze-thaw cycles. Lyophilized state: 36 months at -20°C to -80°C After reconstitution and under sterile conditions: 6 months at -20°C to -80°C 7-10 days at 2°C to 8°C |