CytoGrow™ Recombinant IL-34 (Human), HEK293 His Tag
Recombinant human IL-34 is a glycoprotein cytokine expressed in HEK293 cells and engineered with a C-terminal His tag to facilitate purification and detection. Expression in HEK293 ensures human-like post-translational modifications, including proper glycosylation, enhancing protein stability and bioactivity.
IL-34 functions as a ligand for the colony-stimulating factor-1 receptor (CSF-1R) and plays a critical role in the differentiation, survival, and function of monocytes and macrophages. It is involved in immune regulation, inflammation, and tissue homeostasis. The His-tagged recombinant IL-34 is widely used in receptor binding assays, signaling studies, and macrophage biology research.
Specifications
Synonym: | |
Species: | Human |
Expression System: | HEK293 |
Endotoxin: | ≤10 EU/mg |
Appearance: | White powder, colorless liquid after reconstitution |
Formulation | Lyophilized from a 0.2 μm filtered solution containing PBS 5% mannitol, and 0.01% Tween 80 |
Reconstitution: | Recommended to redissolve in sterile deionized water |
Shipping: | Ships overnight |
Storage and Stability: | Store in a manual defrost freezer and avoid repeated freeze-thaw cycles. Lyophilized state: 36 months at -20°C to -80°C After reconstitution and under sterile conditions: 6 months at -20°C to -80°C 7-10 days at 2°C to 8°C |