LIF (Human), Recombinant Protein, E. coli, Tag Free
Premium CytoGrow™ growth factor suitable for stem cell and iPSC culture, pluripotency maintenance, developmental biology, immune regulation, neurobiology research
CytoGrow™ Recombinant LIF (Human), E. coli, Tag Free
Recombinant human leukemia inhibitory factor (LIF) is produced in E. coli in a tag-free format, yielding a biologically active cytokine suitable for research applications. LIF is a member of the IL-6 cytokine family and plays a crucial role in cell differentiation, survival, and immune regulation.
In humans, LIF is secreted by a variety of tissues including the endometrium, placenta, and activated immune cells. It is best known for maintaining the pluripotency and self-renewal of embryonic stem cells through the LIF/STAT3 signaling pathway. Beyond stem cell biology, LIF contributes to inflammation, hematopoiesis, neurogenesis, and bone metabolism. Recombinant LIF is widely used in stem cell culture, regenerative medicine research, and immune modulation studies.
| Synonym: | |
| Species: | Human |
| Expression System: | E. coli |
| Endotoxin: | ≤100 EU/mg |
| Appearance: | White powder, colorless liquid after reconstitution |
| Formulation | Lyophilized from a 0.22 μm filtered solution containing 10 m M PB, 5% Trehalose, and 0.01% Tween 80 |
| Reconstitution: | Recommended to redissolve in sterile deionized water |
| Shipping: | Ships overnight |
| Storage and Stability: | Store in a manual defrost freezer and avoid repeated freeze-thaw cycles. Lyophilized state: 36 months at -20°C to -80°C After reconstitution and under sterile conditions: 6 months at -20°C to -80°C 7-10 days at 2°C to 8°C |
Resources
Booklet – CytoGrow Growth Factors
Material Safety Data Sheet (MSDS)
Data and Bioactivity
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| Size | 1 μg, 10 µg, 50 μg, 1 mg, 10 mg, 100 mg, 1 g, 1 mL, 10 mL |
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