Recombinant human Noggin is expressed in CHO cells to ensure proper folding and authentic mammalian post-translational modifications. This tag-free protein retains the native structure and high bioactivity of human Noggin, making it suitable for diverse applications in developmental biology and cell signaling research.

Noggin is a secreted glycoprotein that functions as an antagonist of bone morphogenetic proteins (BMPs). By binding to BMPs, Noggin inhibits their interaction with receptors, playing a critical role in regulating embryonic development, tissue differentiation, and organogenesis. Recombinant human Noggin is widely used in studies involving stem cell differentiation, BMP pathway modulation, and developmental biology.