CytoGrow™ Recombinant Noggin (Human), CHO, Tag Free
Recombinant human Noggin is expressed in CHO cells to ensure proper folding and authentic mammalian post-translational modifications. This tag-free protein retains the native structure and high bioactivity of human Noggin, making it suitable for diverse applications in developmental biology and cell signaling research.
Noggin is a secreted glycoprotein that functions as an antagonist of bone morphogenetic proteins (BMPs). By binding to BMPs, Noggin inhibits their interaction with receptors, playing a critical role in regulating embryonic development, tissue differentiation, and organogenesis. Recombinant human Noggin is widely used in studies involving stem cell differentiation, BMP pathway modulation, and developmental biology.
Specifications
Synonym: | Noggin; NOG |
Species: | Human |
Expression System: | Chinese Hamster Ovary cell line (CHO) |
Endotoxin: | ≤10 EU/mg |
Appearance: | White powder, colorless clear liquid after reconstitution |
Formulation | Lyophilized from a 0.22 μm filtered solution containing PBS, 5% mannitol and 0.01% Tween 80 |
Reconstitution: | Recommended to redissolve in sterile deionized water |
Shipping: | Shipped with ice pack |
Storage and Stability: | Lyophilized state: 36 months at -20°C to -80°C After reconstitution and under sterile conditions: 6 months at -20°C to -80°C 7-10 days at 2°C to 8°C Store in a manual defrost freezer and avoid repeated freeze-thaw cycles. |
Data and Bioactivity
