Noggin (Mouse), Recombinant Protein, CHO, Tag Free
Premium CytoGrow™ growth factor suitable for mouse developmental biology, stem cell differentiation, BMP pathway studies, and tissue engineering research.
CytoGrow™ Recombinant Noggin (Mouse), CHO, Tag Free
Recombinant mouse Noggin is expressed in CHO cells to ensure proper folding and authentic mammalian post-translational modifications. This tag-free protein retains the native structure and high bioactivity of mouse Noggin, making it suitable for diverse applications in developmental biology and cell signaling research.
Noggin is a secreted glycoprotein that functions as an antagonist of bone morphogenetic proteins (BMPs). By binding to BMPs, Noggin inhibits their interaction with receptors, playing a critical role in regulating embryonic development, tissue differentiation, and organogenesis. Recombinant mouse Noggin is widely used in studies involving stem cell differentiation, BMP pathway modulation,
| Synonym: | Noggin; NOG |
| Species: | Mouse |
| Expression System: | Chinese Hamster Ovary cell line (CHO) |
| Endotoxin: | ≤10 EU/mg |
| Appearance: | White powder, colorless clear liquid after reconstitution |
| Formulation | Lyophilized from a 0.2 μm filtered solution containing PBS, 5% mannitol and 0.01% Tween 80 |
| Reconstitution: | Recommended to redissolve in sterile deionized water |
| Shipping: | US - Ships overnight |
| Storage and Stability: | Lyophilized state: 36 months at -20°C to -80°C After reconstitution and under sterile conditions: 6 months at -20°C to -80°C 7-10 days at 2°C to 8°C Store in a manual defrost freezer and avoid repeated freeze-thaw cycles. |
Data and Bioactivity
The activity is measured by its ability to inhibit 5.0 ng/mL of BMP-4–induced alkaline phosphatase production in ATDC-5 chondrogenic cells. The data presents a head-to-head comparison with industry-leading competitors.
| Size | 1 μg, 10 µg, 50 μg, 1 mg, 10 mg, 100 mg, 1 g, 1 mL, 10 mL |
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