NT-3 (Human), Recombinant Protein, HEK293, Tag Free

Premium CytoGrow™ growth factor is suitable for neuroscience research, neuronal culture and differentiation, neuroregeneration studies, synaptic function, and plasticity models.

CytoGrow™ Recombinant NT-3 (Human), HEK293, Tag Free

Recombinant human neurotrophin-3 (NT-3) is produced in HEK293 cells in a tag-free format, ensuring correct folding and human-like post-translational modifications. NT-3 is a member of the neurotrophin family, which also includes NGF, BDNF, and NT-4/5, and plays a vital role in the development, survival, and differentiation of neurons.

In humans, NT-3 binds primarily to the TrkC receptor, with additional interactions with TrkA and TrkB, activating signaling pathways that regulate neuronal survival, axonal growth, and synaptic plasticity. NT-3 is critical for sensory and motor neuron development, and also contributes to synaptic refinement in the central nervous system. Recombinant NT-3 is widely used in neuroscience research, neuronal culture systems, neuroregeneration models, and studies on synaptic function and plasticity.

Specifications 

Synonym: 
Species:Human
Expression System:HEK 293
Endotoxin:≤20 EU/mg
Appearance:White powder, colorless liquid after reconstitution
Formulation Lyophilized from a 0.22 μm filtered solution containing PBS, 5% Mannitol, 0.01% Tween 80
Reconstitution:Recommended to redissolve in sterile deionized water
Shipping:Ships overnight
Storage and Stability:Store in a manual defrost freezer and avoid repeated freeze-thaw cycles.

Lyophilized state:
36 months at -20°C to -80°C

After reconstitution and under sterile conditions:
6 months at -20°C to -80°C
7-10 days at 2°C to 8°C

Resources


Booklet – CytoGrow Growth Factors

Product Data Sheet

Material Safety Data Sheet (MSDS)

Frequently Asked Questions 

Data and Bioactivity

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Size

1 μg, 10 µg, 50 μg, 1 mg, 100 mg, 1 g, 1 mL, 10 mL