PDGF-BB (Human), Recombinant Protein, CHO, Tag Free
Premium CytoGrow™ growth factor suitable for angiogenesis and fibrosis studies, wound healing and tissue repair models, stem cell and smooth muscle biology, regenerative medicine and tissue engineering
CytoGrow™ Recombinant PDGF-BB (Human), CHO, Tag Free
Recombinant human platelet-derived growth factor-BB (PDGF-BB) is produced in CHO cells in a tag-free format, ensuring proper folding, dimerization, and human-like post-translational modifications. PDGF-BB is a potent mitogen and chemoattractant that plays a key role in cell proliferation, migration, angiogenesis, and tissue repair.
In humans, PDGF-BB is secreted as a homodimer and binds to PDGF receptor-α and PDGF receptor-β, activating signaling pathways that regulate fibroblast, smooth muscle cell, and mesenchymal stem cell functions. It is essential in wound healing, vascular remodeling, and development. Recombinant PDGF-BB is widely used in studies of angiogenesis, fibrosis, tissue engineering, and regenerative medicine.
| Synonym: | |
| Species: | Human |
| Expression System: | Chinese Hamster Ovary (CHO) |
| Endotoxin: | ≤10 EU/mg |
| Appearance: | White powder, colorless liquid after reconstitution |
| Formulation | Lyophilized from a 0.22 μm filtered solution containing PBS, 5% Mannitol, and 0.01% Tween 80 |
| Reconstitution: | Recommended to redissolve in sterile deionized water |
| Shipping: | Ships overnight |
| Storage and Stability: | Store in a manual defrost freezer and avoid repeated freeze-thaw cycles. Lyophilized state: 36 months at -20°C to -80°C After reconstitution and under sterile conditions: 6 months at -20°C to -80°C 7-10 days at 2°C to 8°C |
Resources
Booklet – CytoGrow Growth Factors
Material Safety Data Sheet (MSDS)
Data and Bioactivity
| Size | 1 μg, 10 µg, 50 μg, 1 mg, 10 mg, 100 mg, 1 g, 1 mL, 10 mL |
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