TPO (Human), Recombinant Protein, CHO, Tag Free
Premium CytoGrow™ growth factor suitable for hematopoiesis research, platelet biology, thrombocytopenia treatment development, and regenerative medicine.
CytoGrow™ Recombinant TPO (Human), CHO, Tag Free
Recombinant human Thrombopoietin (TPO) is expressed in CHO cells to ensure proper folding and authentic mammalian post-translational modifications. This tag-free protein retains the native structure and high bioactivity of human TPO, making it suitable for diverse applications in hematology and stem cell research.
TPO is a critical growth factor that regulates the production and differentiation of megakaryocytes and platelets. It binds to the c-Mpl receptor to stimulate platelet formation and maintain hematopoietic stem cell populations. Recombinant human TPO is widely used in studies of thrombopoiesis, bone marrow biology, and therapeutic development for platelet-related disorders.
| Synonym: | rHuThrombopoietin/TPO; TPO |
| Species: | Human |
| Expression System: | Chinese Hamster Ovary cell line (CHO) |
| Endotoxin: | ≤10 EU/mg |
| Appearance: | White powder, colorless liquid after reconstitution |
| Formulation | Lyophilized from a 0.2 μm filtered solution containing PBS, 5% mannitol, and 0.01% Tween 80 |
| Reconstitution: | Recommended to redissolve in sterile deionized water |
| Shipping: | US - Ships overnight |
| Storage and Stability: | Store in a manual defrost freezer and avoid repeated freeze-thaw cycles. Lyophilized state: 36 months at -20°C to -80°C After reconstitution and under sterile conditions: 6 months at -20°C to -80°C 7-10 days at 2°C to 8°C |
Data and Bioactivity
Measured in a cell proliferation assay using Mo7e cells. The ED50 for this effect is ≤1.0 ng/mL. The data presents a head-to-head comparison with industry-leading competitors.
| Size | 1 μg, 10 µg, 50 μg, 1 mg, 10 mg, 100 mg, 1 g, 1 mL, 10 mL |
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