VEGF121 (Human), Recombinant Protein, CHO, Tag Free
Premium CytoGrow™ growth factor suitable for angiogenesis and vascular biology studies, tumor vascularization models, tissue engineering and regenerative medicine, wound healing research
CytoGrow™ Recombinant VEGF 121 (Human), CHO, Tag Free
Recombinant human vascular endothelial growth factor 121 (VEGF121) is produced in CHO cells in a tag-free format, ensuring correct folding and human-like post-translational modifications. VEGF121 is a naturally occurring isoform of VEGF-A generated by alternative splicing, functioning as a potent pro-angiogenic factor that regulates vascular development and endothelial cell biology.
In humans, VEGF121 binds to VEGF receptors VEGFR-1 (Flt-1) and VEGFR-2 (KDR/Flk-1), stimulating endothelial cell proliferation, migration, survival, and new blood vessel formation. Unlike longer VEGF isoforms, VEGF121 lacks heparin-binding domains, making it freely diffusible and highly bioavailable in the extracellular space. Recombinant VEGF121 is widely used in angiogenesis research, vascular biology studies, tissue engineering, and cancer models.
| Synonym: | |
| Species: | Human |
| Expression System: | Chinese Hamster Ovary (CHO) |
| Endotoxin: | ≤10 EU/mg |
| Appearance: | White powder, colorless liquid after reconstitution |
| Formulation | Lyophilized from a 0.22 μm filtered solution containing PBS, 5% Mannitol, and 0.01% Tween 80 |
| Reconstitution: | Recommended to redissolve in sterile deionized water |
| Shipping: | Ships overnight |
| Storage and Stability: | Store in a manual defrost freezer and avoid repeated freeze-thaw cycles. Lyophilized state: 36 months at -20°C to -80°C After reconstitution and under sterile conditions: 6 months at -20°C to -80°C 7-10 days at 2°C to 8°C |
Resources
Booklet – CytoGrow Growth Factors
Material Safety Data Sheet (MSDS)
Data and Bioactivity
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| Size | 1 μg, 10 µg, 50 μg, 1 mg, 10 mg, 100 mg, 1 g, 1 mL, 10 mL |
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