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Author Archives: Kyra Baricaua
This study leveraged VitroGel®’s hydrogel system to model the tumor microenvironment and uncover the role of TIMP1 in driving venous invasion in pancreatic cancer. Hydrogel: VitroGel® Hydrogel Matrix (VHM01) Pancreatic ductal adenocarcinoma (PDAC) is characterized by its aggressive nature and poor prognosis, often driven by early vascular invasion and metastasis. In this study, researchers focused […]
VitroGel® IKVAV was a key component that enabled stable vessel formation, proper cellular organization and functional BBB behavior in the 3D microfluidic model. Hydrogel: VitroGel® IKVAV (Cat. No: TWG007) The blood-brain barrier (BBB) presents a major challenge in neuro-oncology and CNS drug development due to its highly selective nature, which restricts the passage of most […]
The future of cancer research is here—and you’re invited to be part of it! Join us at AACR 2025 (American Association for Cancer Research) from April 25-30, 2025, at McCormick Place Convention Center, Chicago, IL, and explore the latest advancements in cancer research, discover innovative solutions, and connect with our team of experts. Click to expand to […]
Eligibility & Submission Rules: Applicants may submit only one entry per person for this travel award. Submissions for multiple events, are not permitted and will result in disqualification. Duplicate entries (e.g., submissions under different email addresses) will be voided. Four (4) applicants will be selected randomly per event. Terms and Conditions Apply. To apply, please […]
VitroGel® Hydrogel Matrix enables the controlled delivery of bioactive Qu-SeNPs, accelerating bone defect healing and enhancing therapeutic potential for regenerative medicine. Hydrogel: VitroGel® Hydrogel Matrix (Cat. No: VHM01) The development of biomimetic hydrogels has significantly advanced the field of regenerative medicine by providing an extracellular matrix-like environment that supports cell survival and function. In bone […]
Abstract: The invasive nature of cancer, driven by epithelial-to-mesenchymal transition (EMT), is a critical process influenced by external cues from the tumor microenvironment, such as extracellular matrix (ECM) composition. The ECM primes cells for EMT and metastasis, making it a key topic in understanding disease progression. For example, in glioblastoma multiforme (GBM), a grade IV […]
VitroGel® supports 3D spheroid models for evaluating basroparib’s efficacy in overcoming MEK inhibitor resistance in KRAS-mutated colorectal cancer. Hydrogel: VitroGel® 3D (Cat. No: TWG001) The study on basroparib’s role in overcoming MEK inhibitor resistance in KRAS-mutated colorectal cancer (CRC) highlights the importance of innovative in vitro models that accurately recapitulate tumor microenvironments. Using VitroGel, a […]
VitroINK® provided a xeno-free, structurally supportive bioink that enabled the precise 3D bioprinting of a functional testis model, facilitating cell viability, maturation, and in vitro spermatogenesis research. Fertility preservation following pediatric cancer therapy has become a critical area of research, as over 80% of childhood cancer survivors reach adulthood, yet up to 66% of male […]
VitroGel® 3D provided a scaffold-free yet supportive matrix that stabilized adipose organoids for imaging and analysis, enhancing the reliability of in vitro obesity research. Hydrogel:VitroGel® 3D (Cat. No: TWG001) Obesity and metabolic diseases remain urgent global health challenges, yet studying human adipose tissue in vitro is complicated by the limitations of 2D cultures and scaffold-based […]
