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Author Archives: Kyra Baricaua
Using VitroGel® to model tumor–stroma crosstalk in 3D and uncover new therapeutic targets in skin cancer. Solar UV-induced skin cancers, like cutaneous squamous cell carcinoma (cSCC), are driven not only by cancer cells themselves but also by their interaction with surrounding fibroblasts. Traditional 2D cultures fail to replicate this complex tumor–stroma communication, limiting our understanding […]
VitroGel® and its Cell Recovery Solution streamline 3D culture and cell isolation for high-impact tumor microenvironment studies. Understanding the mechanisms driving nasopharyngeal carcinoma (NPC) progression and metastasis requires physiologically relevant in vitro models. In this study, researchers investigated how FLT1-enriched extracellular vesicles (EVs) mediate a pro-metastatic feedback loop between NPC cells and endothelial cells. To […]
VitroGel® ORGANOID-3 enabled the successful creation of patient-derived 3D meningioma models that closely mimicked primary tumor structure, biomarker expression, and epigenetic profiles in a xeno-free, reproducible system. Meningioma treatment faces significant hurdles, particularly due to the lack of effective preclinical models that mimic the complex biology of individual tumors. Traditional two-dimensional (2D) cell cultures oversimplify […]
Monmouth Junction, NJ – TheWell Bioscience Inc., a leader in advanced 3D cell culture platforms for precision medicine, cell therapy, and biomanufacturing, announces the launch of VitroGel® NEURON, a groundbreaking synthetic and xeno-free hydrogel specifically engineered to overcome the limitations of animal-derived matrices by supporting both 3D and 2D neuronal culture and serving as an […]
VitroGel® NEURON is a xeno-free hydrogel designed to closely mimic the native extracellular matrix, supporting the growth, differentiation, and maturation of neuronal cells. With its user-friendly, ready-to-use formulation, scientists can seamlessly transition between 2D and 3D cultures without the need for animal-derived components — significantly improving experimental consistency and translational relevance.
Discover why VitroGel® is the leading animal-free hydrogel.
In April 2025, the U.S. Food and Drug Administration (FDA) announced a groundbreaking initiative to phase out the animal testing requirement for monoclonal antibodies and other drugs. This marked a significant milestone in the advancement of preclinical research. Experts from regulatory agencies, academia, and industry worldwide convened to promote the adoption of New Approach Methodologies […]
