Advanced 3D Cell Models for Lab Automation
Integrating advanced 3D cell models, such as organoids and tumoroids, with lab automation technology can streamline workflows, reduce human error, and ensure the reproducibility of handling these complex models. This approach is ideal as it enhances data reliability while enabling efficient high-throughput cell culture and screening. Learn how the VitroGel® hydrogel overcomes current animal-based ECM when adapting for laboratory automation.
Challenges of using animal-based ECM in laboratory automation
Using traditional animal-based ECM poses many challenges and limitations that can affect workflow, results, and scalability:
Complex Handling Requirements and Incompatibility with Automation:
Animal-based ECMs require low temperatures and precise handling and are challenging to integrate with automated systems designed for speed and uniformity. Lab automation equipment will require special retrofitting to adapt to cold temperature handling. Any fluctuation in temperature will cause gelation, leading to tip clogging.
Batch-to-Batch Variability and Reproducibility Issues:
The inconsistent quality between the batches of animal-based ECM leads to unreliable results, making it difficult for a more accurate study.
Ethical, Regulatory, and Contamination Concerns:
Using animal-derived materials raises ethical, regulatory, and contamination risks, limiting their suitability for pharmaceutical and clinical research.
VitroGel®: the right hydrogel for enabling laboratory automation
VitroGel® hydrogel is room temperature stable, and its unique shear-thinning and rapid recovery rheological properties allow for easy dispensing in laboratory automation and high throughput applications.
Room temperature stable for sample preparation.
No pipette tip clogging issues.
Long-term injectable status ensuring accurate pipetting and transfer of hydrogel.
Synthetic, xeno-free system with batch-to-batch consistency.
Excellent when used with the VitroPrime™ Spread-Attach Plate
Applicable for both VitroGel® and VitroINK®
VitroGel® works with many types of high-throughput equipment
Automatic
multiple-channel pipette
Bench-top
liquid handling machine
Fully automated
liquid handling system
Microarray: non-contact
dispensing system
VitroPrime™ Spread-Attach Plate: Excellent for hydrogel lab automation
VitroPrime™ Ultra-Low Attachment Plate supports automated imaging systems
Works seamlessly with imaging platforms including Incucyte, Molecular Devices, and more.
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Featured Products
Hydrogels - Ready-To-Use
ready-to-use, xeno-free (animal origin-free) biofunctional hydrogel system
Bioinks
Ready-to-use bioinks for 3D bioprinting
Cell Culture Plates
Unique surface treated for superior hydrogel spreading, adherence, and uniform surface.
Biomarkers
Versatile, live/dead cell viability analysis for 3D and 2D cell culture. IN STOCK
Cell Harvesting Solution
Non-enzymatic cell harvesting solution to recover cells/organoids from hydrogel or an animal-based ECM within 15 minutes. Improved formulation over VitroGel® Cell Recovery Solution.
