A comparison study of VitroGel® and Matrigel® for long-term neuron maturation and survival in vitro Comparison Study Martin L. Tomov Stanley Center; Broad Institute of MIT and Harvard Introduction Three-dimensional (3D) tissue cultures have numerous advantages compared to traditional two-dimensional (2D) cultures [1; 5]. Minimizing exposure to hard surfaces can improve cell maturation and survival […]
Application Note TheWell Bioscience Inc. Introduction In vitro assays have become increasingly popular in drug discovery applications because of their high throughput functionality and cost-effectiveness in conducting optimization and preclinical validation. Three-dimensional (3D) culture assays have become especially popular because compared to traditional two-dimensional (2D) cell culture, 3D culture provides a more physiologically relevant environment […]
Application Note TheWell Bioscience Inc. Introduction 3D culture has become the standard for studying complex systems, such as the tumor microenvironment (TME), in an in vitro setting. These systems allow for insight into the cell-cell interactions and communications that occur in vivo. The use of 3D matrices mimics the complex TME (2) and is even […]
