Maternally derived adipose stem cells have emerged as a possible solution to the common immunological rejection observed in fetal repair surgeries. Institution: Showa University School of Medicine Team: Akihiro Kawashima*, Rika Yasuhara, Ryosuke Akino, Kenji Mishima, Michiko Nasu, Akihiko Sekizawa Application: In vivo utilization of VitroGel RGD to study neuronal differentiation capacity Disease model: Neurometabolic […]
VitroGel® RGD enhances stem cell transplantation to treat intervertebral disc degeneration using rat models, laying new foundations in the movement toward cell-based tissue therapies. Institution: Dalian Medical University, Clinical Medical College of Yangzhou University Team: Feng Wang, Li-ping Nan, Shi-feng Zhou, Yang Liu, Ze-yu Wang, Jing-cheng Wang, Xin-min Feng *, and Liang Zhang Application: 3D […]
In vitro three-dimensional culture of murine ovarian follicles in the VitroGel demonstrates superior morphology and growth compared to other biomaterials and 2D culture. Institution: Seoul National University, Eulji University Team: Eun Jung Kim, Chungmo Yang, Jaewang Lee, Hye Won Youm, Jung Ryeol Lee *, Chang Suk Suh, Seok Hyun Kim Application: 3D follicle culture Disease […]
Manipulation of the adenosine metabolite ADK-L may offer a way to modulate cell invasion and proliferation of breast cancer cells, offering a possible therapeutic solution to aggressive breast cancers. Institution: Legacy Research Institute, Mid-Columbia Medical Center Team: Bahar Shamloo*, Nandita Kumar, Randall H. Owen, Jesica Reemmer, John Ost, R. Serene Perkins, and Hai-Ying Shen* Application: […]
Cancer cell-derived and plasma-derived oncogenic extracellular vesicles uniquely carry the cell cycle activator c-Myc and promote cell cycle upregulation and cluster formation of healthy cells in a 3D microenvironment. Institution: Fondazione IRCCS Istituto Nazionale dei Tumori, Istituto di scienze e tecnologie Molecolari CNR Team: Cristina Borzi, Linda Calzolari, Anna M. Ferretti, Laura Caleca, Ugo Pastorino, […]
Introducing OSA 1777, a cell line derived from recurring osteosarcoma, which unlike existing cell lines, forms spheroids in 3D culture reminiscent of osteosarcoma tumors. Institution: David Geffen School of Medicine, University of California, HRH Princess Chulabhorn College of Medical Science, Chulabhorn Royal Academy, Chinese Academy of Medical Sciences and Peking Union Medical College Team: Pichaya […]
New mechanistic insights into the tumorigenesis of DIPG yield a novel potential treatment: PPM1D inhibitors Institution: Emory School of Medicine Team: Mwangala Precious Akamandisa, Kai Nie, Rita Nahta, Dolores Hambardzumyan, and Robert Craig Castellino * Application: Use of VitroGel 3D for in vivo studies and assessing cell survival Disease model: Diffuse intrinsic pontine glioma (DIPG) […]
Three-dimensional hydrogels help to unravel the role and mechanism of action of BST-2 in breast cancer growth and metastasis and introduce a putative new therapy Institution: Carver College of Medicine, University of Iowa, Stony Brook University, Stanford University School of Medicine Team: Wadi D. Mahauad-Fernandez, Chioma M. Okeoma * Application: 3D tissue model to evaluate […]
Repressing CDK9 blocks cell spheroid formation in 3D culture and delays growth of synovial sarcoma cells Institution: Carver College of Medicine, University of Iowa, Stony Brook University, Stanford University School of Medicine, Atta-ur-Rahman School of Applied Bio sciences, National University of Sciences and Technology Team: Wadi D. Mahauad-Fernandez, Wasifa Naushad, Tyler D. Panzner, Amani Bashir, […]
The biocompatible and injectable VitroGel hydrogel culture system enhances pulp-dentin regeneration and has the potential for chair-side regenerative endodontic procedures Institution: The Fourth Military Medical University, China Medical University Team: Min Xiao, Jun Qiu, Rong Kuang, Beidi Zhang, Wei Wang*, Qing Yu * Application: In vivo utilization to study biocompatibility and differentiation potential of primary […]
