Category Archives: Research Highlights

Trk-ing down castration-resistant prostate cancer: 3D organoid models reveal a new drug target for an aggressive form of prostate cancer.

Three-dimensional cancer-derived organoids introduce TrkA as a promising new biomarker and target for a nearly incurable disease. Institution: University of Campania Team: Marzia Di Donato, Gustavo Cernera, Antimo Migliaccio*and Gabriella Castoria * Application: 3D tissue model to evaluate role of a gene in tumor progression Disease model: Prostate cancer Cell types: Human PC-derived DU145 cells […]