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VitroGel®: Xeno-free Hydrogel for Advancing Organoid Research
Organoids have emerged as powerful, physiologically relevant models that bridge the gap between traditional 2D culture and in vivo systems. Derived from stem cells or patient tissues, these complex structures mimic the architecture and function of real organs, making them invaluable tools for disease modeling, regenerative medicine, and drug discovery.
However, reliance on animal-derived extracellular matrices (ECMs) remains a major challenge in organoid culture.
Limitations of Using Animal-Based ECM
in Organoid Research
- Reduced viability and higher loss.
- Incomplete polarity flipping.
- Cannot support long-term culture.
- Time-consuming and requires expertise.
The Solution:
VitroGel® ORGANOID
- Yields high organoid viability.
- Naturally supports apical-out morphology.
- Enables long-term organoid culturing.
- Easy to use. 20-min protocol.
VitroGel® ORGANOID: A revolutionary hydrogel-based scale-up system for excellent organoid formation.
Xeno-free and Synthetic
100% synthetic. Animal & human origin-free, biofunctional hydrogel for organoid formation.
Supports multiple organoid types
Supports a wide range of organoids from patient-derived samples, stem cells, tissues, co-culture, and PDX resources
Supports apical-out organoid
Naturally supports apical-out organoids and enables long-term organoid culturing..
Easy cell harvesting
Easy and efficient cell harvesting by either centrifuge or the non-enzymatic VitroGel® Organoid Recovery Solution.
Room-temperature stable
Simple, fast, and easy-to-use. Room temperature protocol/operation. No ice bucket.
Lab automation-friendly
Room temperature stable for easy pipetting. Ideal for automation and high-content screening.
Explore the Multiple Applications using VitroGel® ORGANOID
Patient-Derived Organoid/Tumoroid & Tissue Explant (Ex-vivo)
VitroGel® ORGANOID provides an optimal xeno-free environment for long-term culture, preserving the phenotypical properties of patient-derived organoids, tumoroids, and ex vivo tissue explants for weeks or even months.
iPSC-Derived
Organoid
Designed to support both 2D maintenance and 3D scale-up, VitroGel® ORGANOID provides a physiologically relevant matrix facilitating efficient differentiation, expansion, and tissue maturation.
Organoid Co-culture
VitroGel® ORGANOID enables a seamless co-culture of organoids with immune cells, supporting immune cell penetration and interaction with organoids/tissue fragments within the matrix.
iPSC-Derived
Organoid
Designed to support both 2D maintenance and 3D scale-up, VitroGel® ORGANOID provides a physiologically relevant matrix facilitating efficient differentiation, expansion, and tissue maturation.
