TheWell Bioscience 2025: A Breakthrough Year in 3D Cell Culture Innovation

TheWell Bioscience 2025: A Breakthrough Year in 3D Cell Culture Innovation

2025 was a transformative year for TheWell Bioscience, marked by strong execution across innovation, market expansion, and community engagement. Through pioneering product launches, we established the industry’s most comprehensive end-to-end xeno-free 3D cell culture platform—positioning the company for sustained growth in advanced translational research markets.

By removing animal-derived inputs and eliminating batch-to-batch variability, our technology delivers a fully defined, ethical, and highly scalable solution for complex 3D modeling, addressing critical reproducibility and regulatory challenges faced by researchers and biopharma partners.

With continued investment in platform innovation and strategic engagement across the scientific ecosystem, TheWell Bioscience has solidified its leadership in xeno-free 3D cell culture and is well positioned to capture expanding opportunities in next-generation drug discovery and development.

Our 2025 Milestones:

117 New Publications for 2025

Our xeno-free system has now been featured in 330 peer-reviewed studies worldwide, with each study reflecting 2–3 years of dedicated scientific work—a powerful testament to trust and proven performance.

This also reinforces our leadership in the synthetic hydrogel market, as measured by publication volume.

Explore all the publications here ↗ 

Launched 10 Innovative Product for 3D Cell Culture

Expanded our innovation portfolio to deliver a truly complete, end-to-end 3D cell culture platform
, seamlessly integrating new solutions with our existing offerings to support the full cell culture research workflow that aligns with the NAMs initiative. 

Key launches included the industry’s first synthetic hydrogel optimized for both 3D and 2D neuron culture, alongside a xeno-free cell culture medium, ready-to-use growth kits, and an ultra-low attachment plate, collectively enabling greater reproducibility, scalability, and translational relevance.

VitroGel® NEURON

The first-of-its-kind synthetic, xeno-free hydrogel specifically engineered to support both 2D and 3D neuronal culture and in vivo delivery. Learn More > 

VitroGel® Glioblastoma (GBM) Xeno-Free EMT Kit

Ready-to-use kit for 3D GBM tumoroid formation. Learn More > 

RocketCell™ NSC Xeno-Free Complete Growth Kit

All-in-one, ready-to-use kit for 3D and 2D neural stem cell culture. Learn More > 

RocketCell™ 3D iPSC Xeno-Free Complete Growth Kit

An all-in-one optimized kit for 3D expansion of pluripotent stem cells. Learn More > 

CytoGrow™ Growth Factors

Premium quality growth factors with research-friendly price designed to support consistent, high-performance cell culture. Learn More > 

VitroPrime™ Ultra-Low
Attachment Plate

An ultra-low attachment plate that inhibits cell attachment, ideal for 3D spheroid and tumoroids/organoid culture.
Learn More > 

10 New Patent Applications

These newly submitted patents further strengthen TheWell Bioscience’s intellectual property portfolio, reinforcing our commitment to delivering a comprehensive, end-to-end 3D cell culture platform.

Joined Conferences and Facilitated Lunch and Learn Sessions for Community Engagement

Participated in 25 conferences, exhibitions, and scientific events worldwide and locally, showcasing our innovations and connecting with researchers across the 3D cell culture and translational research community.

Organized our first two Lunch & Learn sessions at EMD Serono and Penn State Health. The session brought together researchers and industry professionals to explore our xeno-free 3D cell culture solutions, share best practices, and foster knowledge exchange within the scientific community.

Hosted Webinars to Advance the Translation of Cutting-edge Research

TheWell Bioscience hosted three educational webinars showcasing the versatility of xeno-free, biofunctional VitroGel® across multiple research applications. By engaging researchers, industry partners, and academic institutions worldwide, the webinars fostered knowledge sharing, encouraged adoption of xeno-free workflows, and reinforced TheWell Bioscience’s role as a thought leader in translational 3D cell culture.

ORGANOID

Culture Apical-Out Organoids with
Xeno-free VitroGel® System

IN VIVO / TISSUE ENGINEERING

EX VIVO

Watch more webinars here↗ 

Completed the GMP Cleanroom Construction

The completion of our GMP cleanroom positions TheWell Bioscience to manufacture GMP-grade products in 2026, strengthening quality compliance and manufacturing readiness.

Established the Complete Xeno-Free Workflow for Multiple Organoid and Tumoroid Models

With a complete workflow—from xeno-free, biofunctional hydrogels and growth kits to 3D culture vessels and downstream analysis—TheWell Bioscience empowers researchers to establish reproducible, end-to-end workflows for organoid and tumoroid models, eliminating animal-derived components and batch-to-batch variability.

Learn how to achieve consistent organoid culture↗ 

Introduced our Brand Ambassador and Mascot Alexis TheWhale 

Introduced Alexis the Whale as our official Brand Ambassador and Laboratory Buddy—quickly becoming a new star within the TheWell Bioscience community. Her enthusiastic reception and widespread acceptance across labs and events highlighted the strong connection and engagement we share with researchers worldwide.

Learn more about Alexis TheWhale and how you can take her home↗ 

Our sincerest THANK YOU to our customers, distributors, and supporters.

Your trust in our vision to deliver an end-to-end, xeno-free platform—one that enhances translational accuracy and accelerates drug discovery and personalized medicine—means a great deal to us. Together, we’re ready to take the next big step forward in 2026.

Warm regards,
TheWell Bioscience