Author Archives: Kyra Baricaua

3D Bioprinting Paves the Way for Fertility Preservation with VitroINK®

VitroINK® provided a xeno-free, structurally supportive bioink that enabled the precise 3D bioprinting of a functional testis model, facilitating cell viability, maturation, and in vitro spermatogenesis research. Fertility preservation following pediatric cancer therapy has become a critical area of research, as over 80% of childhood cancer survivors reach adulthood, yet up to 66% of male […]

Scaffold-Free 3D Adipose Tissue Organoids: Unlocking Obesity Research with VitroGel® 3D

VitroGel® 3D provided a scaffold-free yet supportive matrix that stabilized adipose organoids for imaging and analysis, enhancing the reliability of in vitro obesity research. Obesity and metabolic diseases remain urgent global health challenges, yet studying human adipose tissue in vitro is complicated by the limitations of 2D cultures and scaffold-based models. Traditional methods often fail […]

Advancing Borderline Ovarian Tumor Research: Precision Viability Assessment in Patient-Derived Organoid Models

Biomarker Cyto3D® Live-Dead Assay Kit (Cat. No: BM01) The study explores the application of tumor organoid technology in borderline ovarian tumors (BOT), a category of tumors with limited treatment options and resistance to conventional chemotherapy. Researchers established patient-derived organoids (PDOs) to model BOT and evaluate potential therapeutic compounds, particularly Bractoppin, a BRCA1 carboxy-terminal domain (BRCT) […]

3D Organoids and Talniflumate: A Powerful Duo Against Pancreatic Cancer

Hydrogel: VitroGel® ORGANOID 3  (Cat. No: VHM04-3) Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers, with limited treatment options and poor patient survival rates. A major challenge in treating PDAC is the tumor’s ability to create a protective barrier of mucins, which shields cancer cells from immune attacks and reduces the effectiveness of […]

Revolutionizing Cancer Research: A Patient-Derived Platform to Model Tumor-Immune Interactions

BiomarkerCyto3D® Live-Dead Assay Kit (Cat. No: BM01) Cancer research has long been challenged by the complexity of tumor-immune interactions. Traditional 2D cell cultures and animal models often fail to capture the intricate tumor microenvironment (TME), limiting their relevance to human biology. Patient-derived precision-cut tumor slices (PCTS) offer a promising solution by preserving the tumor’s architecture […]

Game Changer for Lymphoma Therapy Screening

VitroGel® RGD played a key role in preserving tumor architecture for effective drug testing in lymphoma research. Hydrogel: VitroGel® RGD (Cat. No: TWG003) VitroGel® played a The fight against cancer, particularly B-cell lymphomas, is challenged by the complexity of tumor microenvironments and the need for personalized treatment strategies. Traditional models such as cell lines and […]

Prolonged Dexamethasone Delivery Using VitroGel® for Protection Against Cisplatin-Induced Ototoxicity

VitroGel® significantly enhanced the delivery of dexamethasone to the inner ear, providing controlled release and improved protection against cisplatin-induced hearing loss. Hydrogel: VitroGel® RGD (Cat. No: TWG003) VitroGel® played a crucial role in the study by enhancing the local delivery of dexamethasone (Dexa) to the inner ear. It facilitated a controlled and prolonged release of […]

Harnessing Patient-Derived Organoids to Decode Immunotherapy Responses in Colorectal Cancer

VitroGel® revolutionizes colorectal cancer research by creating a xeno-free platform for patient-derived organoids, enabling groundbreaking insights into tumor-immune interactions and immunotherapy responses. Hydrogel: VitroGel® MSC (Cat. No: VHM03) Other VitroGel® option: VitroGel® ORGANOID-3 (Cat. No: VHM04-3) VitroGel® played a crucial role in establishing a patient-derived immunity-organoid interaction platform for colorectal cancer (CRC) research. By providing […]