bFGF/FGF-2 (Eel), Recombinant Protein, E. coli, Tag Free
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CytoGrow™ Recombinant bFGF/FGF-2 (Eel), E. coli, Tag Free
Recombinant eel basic fibroblast growth factor (bFGF), also known as FGF-2, is produced in E. coli in a tag-free format, ensuring high purity and reliable biological activity. bFGF/FGF-2 is a conserved member of the fibroblast growth factor family, playing a crucial role in regulating cell proliferation, differentiation, and survival across diverse species.
In fish and other vertebrates, bFGF binds to fibroblast growth factor receptors (FGFRs) in the presence of heparan sulfate proteoglycans, activating downstream signaling pathways such as MAPK/ERK and PI3K/AKT. These pathways support cell growth, migration, angiogenesis, and tissue repair. bFGF is also important for developmental processes and regeneration, particularly in aquatic species. Recombinant eel bFGF is widely used in cell culture, aquaculture research, developmental biology, and tissue regeneration studies.
| Synonym: | Fibroblast growth factor 2; FGF-2; Basic fibroblast growth factor; bFGF |
| Species: | Eel |
| Expression System: | E. coli |
| Endotoxin: | ≤200 EU/mg |
| Appearance: | White powder, colorless liquid after reconstitution |
| Formulation | Lyophilized from a 0.2 μm filtered solution containing 10 mM PB, 5% Trehalose, and 0.01% Tween 80 |
| Reconstitution: | Recommended to redissolve in sterile deionized water |
| Shipping: | US - Ships overnight |
| Storage and Stability: | Store in a manual defrost freezer and avoid repeated freeze-thaw cycles. Lyophilized state: 36 months at -20°C to -80°C After reconstitution and under sterile conditions: 6 months at -20°C to -80°C 7-10 days at 2°C to 8°C |
Data and Bioactivity
Measured in a cell proliferation assay using NIH3T3 cells.
| Size | 1 μg, 10 µg, 50 μg, 1 mg, 100 mg, 1 g, 1 mL, 10 mL |
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