CytoGrow™ Recombinant FGF-10/KGF2 (Human), E. coli, Tag Free
Recombinant human fibroblast growth factor 10 (FGF-10), also known as keratinocyte growth factor 2 (KGF2), is produced in E. coli in a tag-free format, ensuring high purity and biological activity. FGF-10 is a member of the fibroblast growth factor family and plays a key role in embryonic development, epithelial cell proliferation, and tissue repair, particularly in lung and skin biology.
In humans, FGF-10 primarily binds to the FGFR2b receptor isoform, activating downstream signaling pathways such as MAPK/ERK and PI3K/AKT. These pathways promote epithelial cell proliferation, differentiation, and migration, as well as organogenesis and tissue regeneration. FGF-10 is especially important in lung branching morphogenesis and skin homeostasis. Recombinant FGF-10 is widely used in epithelial biology research, stem cell and organoid culture systems, regenerative medicine, and wound healing studies.
Specifications
| Synonym: | Fibroblast growth factor 10;FGF-10;Keratinocyte growth factor 2;FGF10;KGF-2;KGF2 |
| Species: | Human |
| Expression System: | E. coli |
| Endotoxin: | ≤10 EU/mg |
| Appearance: | White powder, colorless clear liquid after reconstitution |
| Formulation | Lyophilized from a 0.22 μm filtered solution containing 10 mM PB, 5% Trehalose, and 0.01% Tween 80 |
| Reconstitution: | Recommended to redissolve in sterile deionized water |
| Shipping: | US - Ships overnight |
| Storage and Stability: | Store in a manual defrost freezer and avoid repeated freeze-thaw cycles.
Lyophilized state:
36 months at -20°C to -80°C
After reconstitution and under sterile conditions:
6 months at -20°C to -80°C
7-10 days at 2°C to 8°C
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Data and Bioactivity