CytoGrow™ Recombinant FGF-7/KGF (Human), E. coli, Tag Free
Recombinant human fibroblast growth factor 7 (FGF-7), also known as keratinocyte growth factor (KGF), is produced in E. coli in a tag-free format, ensuring high purity and reliable biological activity. FGF-7 is a member of the fibroblast growth factor family and plays a critical role in epithelial cell growth, differentiation, and tissue repair, particularly in skin and mucosal tissues.
In humans, FGF-7 specifically binds to the FGFR2b receptor isoform, activating downstream signaling pathways such as MAPK/ERK and PI3K/AKT. These pathways promote epithelial cell proliferation, migration, and survival, supporting processes such as wound healing and tissue regeneration. FGF-7 is especially important for maintaining epithelial integrity in organs such as the skin, lung, and gastrointestinal tract. Recombinant FGF-7 is widely used in epithelial biology research, stem cell culture systems, tissue engineering, and regenerative medicine applications.
Specifications
| Synonym: | |
| Species: | Human |
| Expression System: | E. coli |
| Endotoxin: | ≤100 EU/mg |
| Appearance: | White powder, colorless liquid after reconstitution |
| Formulation | Lyophilized from a 0.22 μm filtered solution containing 10 mM PB, 5% Trehalose, and 0.01% Tween 80 |
| Reconstitution: | Recommended to redissolve in sterile deionized water |
| Shipping: | US - Ships overnight |
| Storage and Stability: | Store in a manual defrost freezer and avoid repeated freeze-thaw cycles.
Lyophilized state:
36 months at -20°C to -80°C
After reconstitution and under sterile conditions:
6 months at -20°C to -80°C
7-10 days at 2°C to 8°C |
Data and Bioactivity