RANK L (Human), Recombinant Protein, CHO, Tag Free

Premium CytoGrow™ growth factor suitable for immunotherapy research, T-cell activation studies, immune checkpoint modulation, and in vitro/in vivo functional assays.

CytoGrow™ Recombinant RANK L (Human), CHO, Tag Free

CytoGrow™ Recombinant Human RANK L is a high-quality, tag-free protein produced in CHO cells to ensure proper folding, post-translational modifications, and full biological activity. Supplied without any fusion tags, this recombinant protein preserves its native structure and function, making it highly suitable for physiologically relevant research applications.

RANK L plays a central role in bone remodeling, immune regulation, and cell signaling. It binds to its receptor RANK to promote osteoclast differentiation, activation, and survival—making it essential for studies in osteoclastogenesis and bone metabolism. In addition, RANKL signaling is widely studied in cancer biology, particularly in tumor progression, metastasis, and the tumor microenvironment, as well as in immune system interactions.

This recombinant protein is ideal for use in osteoclast differentiation assays, bone biology research, cancer and metastasis studies, and immunology applications. Its high purity, consistent performance, and reliable bioactivity make it a dependable choice for reproducible in vitro experiments and advanced cell culture systems.

Specifications 

Synonym: TRANCE, OPGL, ODF
Species:Human
Expression System:Chinese Hamster Ovary cell line (CHO)
Endotoxin:≤10 EU/mg
Appearance:White powder, colorless clear liquid after reconstitution
Formulation Lyophilized from a 0.22 μm-filtered solution containing PBS, 5% Mannitol and 0.01% Tween80
Reconstitution: Recommended to redissolve in sterile deionized water
Shipping:US - Ships overnight
Storage and Stability:Lyophilized state:
36 months at -20°C to -80°C

After reconstitution and under sterile conditions:
6 months at -20°C to -80°C
7-10 days at 2°C to 8°C

Store in a manual defrost freezer and avoid repeated freeze-thaw cycles.

Resources


Booklet – CytoGrow Growth Factors

Product Data Sheet

Material Safety Data Sheet (MSDS)

Frequently Asked Questions 

Data and Bioactivity

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Size

1 μg, 10 µg, 50 μg, 1 mg, 10 mg, 100 mg, 1 g, 1 mL, 10 mL