Webinars
Developing Robust Three-Dimensional Tumoroid Models with the VitroGel® Glioblastoma Xeno-Free EMT Kit
Learn how a xeno-free 3D platform enables controlled EMT Modeling and GBM tumoroid formation
Glioblastoma multiforme (GBM), the most aggressive form of brain cancer, remains highly challenging to treat, in part due to the protective effects of the blood–brain barrier. However, progress in developing effective therapies is also hindered by inadequate model systems that fail to recapitulate tumor progression, invasion, and epithelial-to-mesenchymal transition (EMT). Traditional 2D cultures and animal-derived matrices often lack physiological relevance and introduce variability, making it difficult to evaluate therapeutic responses in a controlled and reproducible manner.
In this webinar, we introduce the VitroGel® Glioblastoma Xeno-Free EMT Kit, a fully defined 3D cell culture platform designed to generate GBM tumoroids and co-culture models while enabling controlled induction of EMT and long-term culture. This ready-to-use system supports the transition of cell line-based spheroids to structurally complex tumoroids, providing a more physiologically relevant model for studying tumor progression and invasion.
We will demonstrate how this platform enables reproducible long-term tumoroid culture and advanced co-culture models, while maintaining structural integrity and viability. By eliminating animal-derived components, the system improves consistency across experiments and supports more reliable downstream analysis for drug response and disease modeling.
Join us to learn how the VitroGel® Glioblastoma Xeno-Free EMT Kit provides a scalable, xeno-free platform for modeling GBM progression, enabling more predictive and standardized workflows for cancer research and drug discovery.
KEY TAKEAWAYS
- GBM-Specific Xeno-Free EMT Platform: An all-in-one system designed specifically for glioblastoma tumoroid formation and EMT modeling.
- Advanced 3D Tumoroid Model: Generate GBM tumoroids from spheroids using a simple, ready-to-use workflow for drug screening.
- Controlled EMT Induction: Study invasion and tumor progression in a defined 3D microenvironment.
- Scalable & HTS-Compatible: Enable automation and high-throughput screening applications.
PRESENTER
Alejandra Ferrer Diaz Ph.D.
TheWell Bioscience
Business Development Manager
Dr. Alejandra Ferrer Diaz is a Business Development Manager at TheWell Bioscience, where she leads the technical support team. Before transitioning into her current role, she worked as a research scientist at the company, focusing on developing advanced 3D models of cancer and neuronal systems using TheWell Bioscience’s end-to-end, xeno-free platform.
Dr. Ferrer Diaz earned her doctorate from Rutgers University, where her research focused on the epigenetic regulation of breast cancer cell dormancy in the bone marrow microenvironment and on the role of mesenchymal stem cells in this process.
PRODUCT USED:
VitroGel® Glioblastoma Xeno-Free EMT Kit
